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ALDOB Depletion Promotes Hepatocellular Carcinogenesis Through Activating Insulin Receptor Signaling and Lipogenesis

ALDOB Depletion Promotes Hepatocellular Carcinogenesis Through Activating Insulin Receptor Signaling and Lipogenesis

Prof. YIN Huiyong's group from SINH uncovered a mechanism by which loss of ALDOB activates IR signaling primarily through releasing IR/ALDOB interaction to promote DNL and HCC, and highlighted a po...

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Scientists Reveal Key Roles of Arginine Methylation in Global Control of RNA Splicing and Translation

Scientists Reveal Key Roles of Arginine Methylation in Global Control of RNA Splicing and Translation

A research team led by Prof. WANG Zefeng from SINH systematically identified interacting proteins for all human PRMTs and demonstrated their functional importance in mRNA splicing and translation.

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Scientists Discover Novel Oncogenic Driver Gene in Human Lung Cancer

Scientists Discover Novel Oncogenic Driver Gene in Human Lung Cancer

A research team led by Prof. WANG Yuexiang from SINH discovered a novel oncogenic driver gene in human lung cancer. This research showed that biological mechanisms of central precocious puberty are...

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