An unexplained gap in the African/Eurasian fossil record may now be explained thanks to a team of researchers from China, Italy and the United States. Using a novel method called FitCoal (fast infinitesimal time coalescent process), the researchers were able to acc...

A research team led by Prof. HU Guohong from SINH revealed the crucial role of SCUBE2 in regulating bone metastasis of luminal breast cancer, and supports its significance in clinical diagnosis and in bone metastasis treatment.

In a recent study by Prof. HU Guohong's group from SINH and collaborators found that osteoclast-derived IL19 could directly regulate the proliferation of lung cancer cells in bone through tumor-expressed IL20RB. This study elucidated a mechanism of direct osteoclas...

In a study published in Nature Metabolism on Dec. 6th, 2021, researchers from Shanghai Institute of Nutrition and Health of Chinese Academy of Sciences, conducted a large scale investigation with plant-derived medicinal agents, and revealed that a natural compound ...

Researchers from SINH and SIMM of CAS jointly revealed a novel DNA-sensing pathway in aged CD4+ T cells that is independent on cGAS/STING, which promotes T cell activation and proliferation and leads to the development of aging-associated autoimmune diseases.

A recent study by Dr. HU Guohong's group showed that CTSC secretion is associated with breast cancer lung metastasis both in breast cancer cell lines and clinical samples. It revealed that CTSC promotes lung metastasis of breast cancer, by regulating neutrophil inf...